Healing of Carotid Stents: A Prospective Duplex Ultrasound Study

2003 ◽  
Vol 10 (3) ◽  
pp. 636-642 ◽  
Author(s):  
Andrea Willfort-Ehringer ◽  
Ramazanali Ahmadi ◽  
Michael E. Gschwandtner ◽  
Angelika Haumer ◽  
Gottfried Heinz ◽  
...  
2003 ◽  
Vol 10 (3) ◽  
pp. 636-642 ◽  
Author(s):  
Andrea Willfort-Ehringer ◽  
Ramazanali Ahmadi ◽  
Michael E. Gschwandtner ◽  
Angelika Haumer ◽  
Gottfried Heinz ◽  
...  

Purpose: To study the dynamics of carotid stent healing over a 2-year period using duplex ultrasound imaging. Methods: One hundred twelve patients with 121 successfully stented carotid arteries were examined with color-coded duplex ultrasound the day after the stent procedure and at 1, 3, 6, 12, and 24 months in follow-up. The maximal thickness and echogenicity of the layer between the stent and the perfused lumen (SPL) were evaluated. Echogenicity was classified as echogenic if the SPL layer was clearly detected in B mode and echolucent if the SPL layer was barely visible in B mode, its border defined by assistance of color-coded flow. Results: At day 1, an echolucent SPL layer with a median thickness of 0.7 mm was interpreted as a thrombotic layer, which decreased at 1 month to practically zero (i.e., not detectable). In follow-up, increases in thickness (mainly up to 6 months) and echogenicity (up to 12 months) of the SPL layer were interpreted as neointimal ingrowth. At 3, 6, and 12 months, the median maximal thickness of the SPL layer was 0.5 mm, 0.9 mm, and 1.0 mm, respectively, whereas the percentage of patients with an echogenic SPL layer was 27% (32/119), 56% (66/117), and 95% (105/110), respectively, at the same time intervals. No further change was observed at the 24-month examination. Conclusions: Three phases of carotid stent incorporation are defined: (1) an early unstable period soon after stent placement with an echolucent (thrombotic) SPL layer, (2) a moderately unstable phase with ingrowing neointima (1–12 months), and (3) a stable phase from the second year on. These data may indicate the need for different intensities of therapy and surveillance intervals.


2012 ◽  
Vol 19 (6) ◽  
pp. 749-756 ◽  
Author(s):  
Brian Chambers ◽  
Jayne Chambers ◽  
Heather Cameron ◽  
Richard Macdonell

Objectives: We designed a prospective case-control study of patients with clinically isolated syndrome (CIS) and Relapsing–Remitting Multiple Sclerosis (RRMS) with an Expanded Disability Status Score (EDSS) of ≤2, compared with age-and-sex-matched healthy controls, to test the hypothesis that chronic cerebrospinal venous insufficiency (CCSVI) is more prevalent in patients with CIS or mild MS. Methods: All subjects were examined using a Siemens Antares duplex ultrasound machine. The internal jugular, vertebral and intracranial veins were studied in subjects in both supine and sitting postures. The sonographer was blind to the subject’s clinical status. Measures included the criteria proposed by Zamboni and volume flow. Presence of CCSVI was defined as ≥2 Zamboni criteria. Results: Seventy patient-control pairs were recruited, with 11 males and 59 females in each group. Only one subject, a control, satisfied the Zamboni definition of CCSVI; however, 19 patients and 13 controls had abnormalities as defined by Zamboni, the difference largely caused by a higher prevalence in patients of internal jugular vein (IJV) stenosis, defined as a cross-sectional area ≤0.3cm2. This difference disappeared with a more rigorous stenosis definition. Further analysis revealed there was IJV valve variation in seven patients and one control. Conclusions: Our findings indicate that CCSVI, as defined by the Zamboni ultrasound criteria, is not present in CIS and mild RRMS (EDSS ≤2), providing further evidence that CCSVI does not have a causal role in MS; however, we found an apparent increase in IJV variation in patients with CIS or mild MS that would warrant further investigation.


1970 ◽  
Vol 3 (2) ◽  
pp. 63-66
Author(s):  
M Saiful Bari ◽  
Prabir K Das ◽  
Atahar Ali ◽  
SA Nurul Alam ◽  
Mahboob Ali ◽  
...  

Fifty patients with coronary artery disease admitted to the National Institute of Cardiovascular Diseases (NICVD), Dhaka were screened for presence of carotid atherosclerosis by duplex ultrasound study during the period of July ’98 to Aug ’99. Out of 50 patients 34 patients (68%) had carotid lesions and normal carotids found in 16 patients (32%). Age range of patients with and without carotid lesions were 56 ± 5.39 yrs and 47± 7.91 yrs respectively. Out of 34 patients, 30 were male (88.24%) and 4 were female (11.76%). Twenty nine patients (85.29%) were smokers, 22 patients (64.7%) were hypertensive and 9 patients (26.47%) were diabetic. Dyslipidaemia was found in 16 patients (47.06%) and a history of transient ischaemic attack (TIA) was found in 10 patients (29.41%). A coexistent CAD on coronary angiography (CAG) was found in 31 patients (91.17%). (University Heart Journal 2007; 3 : 63-64)


2006 ◽  
Vol 43 (3) ◽  
pp. 488-492 ◽  
Author(s):  
Yehuda G. Wolf ◽  
Zeev Kobzantsev ◽  
Laszlo Zelmanovich

2018 ◽  
Vol 27 (04) ◽  
pp. 185-189 ◽  
Author(s):  
N. Radhakrishnan ◽  
Deepu George ◽  
R. Jayakrishnan ◽  
S. Sumi ◽  
C.C. Kartha

AbstractGiven the high prevalence of chronic venous diseases (CVD), defining criteria to screen patients who are in need for intervention is attaining primacy. An important clinical criterion for treating CVD is incompetence of larger veins. We have assessed the association of size of afflicted veins with disease severity in patients with CVD to define an acceptable criterion to identify patients who need intervention. Demographic characteristics and risk factors were recorded from 6350 patients. Based on physical examination and venous duplex ultrasound study, patients were classified into clinical severity, etiology, anatomy, and pathophysiology (CEAP) classes and grouped according to the size of the veins which had varicosities. Patients with reflux in smaller veins (vein size <4 mm diameter) were considered as type I and those with varicosities in truncal veins (>4 mm diameter) as type II. Risk ratio was determined by multivariate regression analysis. About 47.67% of patients in this study were found to have CEAP class 3 disease. Compared with varicose veins of large truncal veins, patients with varicosities in smaller superficial veins had 2.85-fold (p < 0.01) more risk of edema and 5.71-fold (p < 0.01) higher prevalence of hyperpigmentation. Varicosities in small superficial veins were associated with higher risk of ulceration (odds ratio 3.93, 95% confidence interval 2.51–6.18) compared with truncal vein reflux. Our study reveals that presence of small varicose veins in patients without truncal saphenous reflux involvement is associated with severe manifestations of venous insufficiency such as edema and skin lesions even in the absence of varicosities in truncal saphenous veins.


Clinics ◽  
2010 ◽  
Vol 65 (12) ◽  
pp. 1315-1323 ◽  
Author(s):  
Marcia Maria Morales ◽  
Alexandre Anacleto ◽  
Marcello Azem Buchdid ◽  
Paulo Ricardo Baggio Simeoni ◽  
Sergio Ledesma ◽  
...  

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